Expertise
- Alkylation, Acylation, Halogenations, Amidation, Phosgenations, Condensation, Cyanation, Cyclo-condensation and Formylations.
- Organometallics: Grignard reaction, Organoborane and Silylation reaction.
- Palladium Chemistry: Suzuki, Sonogashira, Heck, kumada, Stille, Carbonylation and Buchwald couplings.
- Hydrogenation using Pd/C, Pt/C, Rh/C and Raney-Ni.
- Metallation – MeLi / n-BuLi / LDA/HMDS.
- Synthesis of Protected N-Terminal & C-Terminal Amino Acids Scaffolds & Di-Peptides and Cyclic Peptides.
- Nucleoside chemistry: Modification of Nucleoside bases, Metal Mediating Reactions on Nucleosides, Modification of Sugar Moieties, Alkylation, Fluorination Reaction at Nucleosides Based and Sugar Moieties.
- Asymmetric syntheses, Chiral alkylation, Chiral Amines syntheis, Enantio selective catalysis, Chiral auxiliaries and Chiral resolution of racemates.
- Wittig Reaction, Mitsunobu Reaction and Vilsmeier-Hack reaction,
- Oxidation – Jones, swern, Dess-Martin Oxidation, KMnO4, NaIO4, Nitric acid
- Reductions – Catalytic, Metal hydrides, High pressure, Metal catalyzed, Birch reductions, Diborane, LAH, DIBAL-H, Catalytic, NaCNBH3.
- Beta-Lactam Antibiotics, Macrolides, Steroids and Prostaglandins
- Special building blocks, API reference standards and Impurity standards.
- Milligram to Kilogram synthesis of complex organic molecules.
- Access to large scale manufacturing."Auto clave" for high pressure and high temperature reactions.
- Low to high temperature chemistry